The acknowledged effects of such PTMs on ATXN2’s purpose and SCA2 pathogenesis stays minimal. In other polyQ diseases, multiple research instructed that proteolytic cleavage of polyQ proteins could play a significant job in pathogenesis [36, 45]. Aligned using this type of notion, the presence of the enriched 42 kDa fragment in https://dantefkpsw.blogspothub.com/27894295/little-known-facts-about-human