The effects dated the specimens to in between 3780 and 3660 BCE. Alkaloid extraction yielded about 2% on the alkaloids which includes mescaline in the two samples. This means that indigenous North Individuals were likely to have utilised peyote since no less than 5-and-a-50 % thousand years in the past. https://peyotecactusseeds.com/product/lophophora-williamsii-seeds/