Listed here, we clearly show that conolidine, a organic analgesic alkaloid used in classic Chinese drugs, targets ACKR3, thus providing more evidence of a correlation between ACKR3 and discomfort modulation and opening alternate therapeutic avenues to the procedure of Long-term pain. Utilized in standard Chinese, Ayurvedic, and Thai drugs. https://chelwoodr481fyi8.yourkwikimage.com/user