Butabarbital decreases results of sufentanil SL by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Intently. Coadministration of CYP3A4 inducers may perhaps minimize sufentanil degrees and efficacy, probably precipitating withdrawal syndrome in patients that have developed Bodily dependence to sufentanil. Discontinuation of concomitantly made use of CYP... https://bjorkw935ogv9.livebloggs.com/profile